General Structure Information
| PDB ID | 2wno |
| HGNC Gene Label(s) | TNFAIP6 |
| Structure Name | x-ray structure of cub_c domain from tsg-6 |
| Resolution | 2.3Å |
| Reference | AUTH D.C.BRIGGS,H.L.BIRCHENOUGH,T.ALI,M.S.RUGG,J.P.WALTHO,AUTH 2 E.IEVOLI,T.A.JOWITT,J.J.ENGHILD,R.P.RICHTER,A.SALUSTRI,AUTH 3 C.M.MILNER,A.J.DAYTITL METAL ION-DEPENDENT HEAVY CHAIN TRANSFER ACTIVITY OF TSG-6TITL 2 MEDIATES ASSEMBLY OF THE CUMULUS-OOCYTE MATRIXREF J.BIOL.CHEM. 2015REFN ESSN 1083-351XPMID 26468290DOI 10.1074/JBC.M115.669838 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 119 |
| Number Of SNVs | 29 |
| Number Of Permutations | 9767 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.273 |
| p-value | 0.401 |
COSMIC
| Number Of Residues | 119 |
| Number Of SNVs | 3 |
| Number Of Permutations | 1 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 29 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.171 |
| p-value | 1.0 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
