General Structure Information
| PDB ID | 2wef |
| HGNC Gene Label(s) | BPNT1 |
| Structure Name | human 3(2), 5-bisphosphate nucleotidase 1 (bpnt1) in complex with amp, po4 and magnesium |
| Resolution | 1.8Å |
| Reference | AUTH M.MOCHE,P.SCHUTZ,C.H.ARROWSMITH,H.BERGLUND,AUTH 2 C.BOUNTRA,R.COLLINS,L.G.DAHLGREN,A.M.EDWARDS,AUTH 3 S.FLODIN,A.FLORES,S.GRASLUND,M.HAMMARSTROM,AUTH 4 A.JOHANSSON,I.JOHANSSON,T.KARLBERG,T.KOTENYOVA,AUTH 5 M.E.NILSSON,T.NYMAN,C.PERSSON,J.SAGEMARK,AUTH 6 H.SCHUELER,M.I.SIPONEN,A.G.THORSELL,L.TRESAUGUES,AUTH 7 S.VAN DEN BERG,J.WEIGELT,M.WELIN,M.WISNIEWSKA,AUTH 8 P.NORDLUNDTITL HUMAN 3(2), 5-BISPHOSPHATE NUCLEOTIDASE 1 (TITL 2 BPNT1) IN COMPLEX WITH AMP, PO4 AND MAGNESIUMREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 303 |
| Number Of SNVs | 68 |
| Number Of Permutations | 24349 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.014 |
| p-value | 0.977 |
COSMIC
| Number Of Residues | 303 |
| Number Of SNVs | 6 |
| Number Of Permutations | 87 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.067 |
| p-value | 0.871 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 68 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.459 |
| p-value | 0.194 |