General Structure Information
| PDB ID | 2vt8 |
| HGNC Gene Label(s) | PSMF1 |
| Structure Name | structure of a conserved dimerisation domain within fbox7 and pi31 |
| Resolution | 2.6Å |
| Reference | AUTH R.J.KIRK,H.LAMAN,P.P.KNOWLES,J.MURRAY-RUST,AUTH 2 M.LOMONOSOV,E.K.MEZIANE,N.Q.MCDONALDTITL STRUCTURE OF A CONSERVED DIMERIZATION DOMAINTITL 2 WITHIN THE F-BOX PROTEIN FBXO7 AND THE PI31TITL 3 PROTEASOME INHIBITOR.REF J.BIOL.CHEM. V. 283 22325 2008REFN ISSN 0021-9258PMID 18495667DOI 10.1074/JBC.M709900200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 140 |
| Number Of SNVs | 42 |
| Number Of Permutations | 10333 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.13 |
| p-value | 0.236 |
COSMIC
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 42 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | -0.318 |
| p-value | 0.474 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
