General Structure Information
| PDB ID | 2vif |
| HGNC Gene Label(s) | SOCS6 |
| Structure Name | crystal structure of socs6 sh2 domain in complex with a c-kit phosphopeptide |
| Resolution | 1.45Å |
| Reference | AUTH F.ZADJALI,A.C.W.PIKE,M.VESTERLUND,J.SUN,C.WU,S.S.LI,AUTH 2 L.RONNSTRAND,S.KNAPP,A.BULLOCK,A.FLORES-MORALESTITL STRUCTURAL BASIS FOR C-KIT INHIBITION BY THETITL 2 SUPPRESSOR OF CYTOKINE SIGNALING 6 (SOCS6)TITL 3 UBIQUITIN LIGASE.REF J.BIOL.CHEM. V. 286 480 2011REFN ISSN 0021-9258PMID 21030588DOI 10.1074/JBC.M110.173526 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 129 |
| Number Of SNVs | 29 |
| Number Of Permutations | 3449 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.131 |
| p-value | 0.022 |