General Structure Information
| PDB ID | 2vcy |
| HGNC Gene Label(s) | MECR |
| Structure Name | crystal structure of 2-enoyl thioester reductase of human fas ii |
| Resolution | 2.41Å |
| Reference | AUTH Z.J.CHEN,R.PUDAS,S.SHARMA,O.S.SMART,A.H.JUFFER,AUTH 2 J.K.HILTUNEN,R.K.WIERENGA,A.M.HAAPALAINENTITL STRUCTURAL ENZYMOLOGICAL STUDIES OF 2-ENOYLTITL 2 THIOESTER REDUCTASE OF THE HUMAN MITOCHONDRIAL FASTITL 3 II PATHWAY: NEW INSIGHTS INTO ITS SUBSTRATETITL 4 RECOGNITION PROPERTIES.REF J.MOL.BIOL. V. 379 830 2008REFN ISSN 0022-2836PMID 18479707DOI 10.1016/J.JMB.2008.04.041 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 332 |
| Number Of SNVs | 99 |
| Number Of Permutations | 43831 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.035 |
| p-value | 0.364 |
COSMIC
| Number Of Residues | 332 |
| Number Of SNVs | 4 |
| Number Of Permutations | 842 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.167 |
| p-value | 0.308 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 99 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.153 |
| p-value | 0.644 |