General Structure Information
| PDB ID | 2rex |
| HGNC Gene Label(s) | RND1 |
| Structure Name | crystal structure of the effector domain of plxnb1 bound with rnd1 gtpase |
| Resolution | 2.3Å |
| Reference | AUTH Y.TONG,W.TEMPEL,L.SHEN,C.H.ARROWSMITH,A.M.EDWARDS,AUTH 2 M.SUNDSTROM,J.WEIGELT,A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF THE EFFECTOR DOMAIN OF PLXNB1 BOUNDTITL 2 WITH RND1 GTPASE.REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 180 |
| Number Of SNVs | 35 |
| Number Of Permutations | 5488 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.032 |
| p-value | 0.944 |
COSMIC
| Number Of Residues | 180 |
| Number Of SNVs | 3 |
| Number Of Permutations | 167 |
| Optimal Distance Threshold | 28.0 |
| K Statistic | 0.333 |
| p-value | 0.413 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 35 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | -0.309 |
| p-value | 0.213 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
