General Structure Information
| PDB ID | 2qg1 |
| HGNC Gene Label(s) | MPDZ |
| Structure Name | crystal structure of the 11th pdz domain of mpdz (mupp1) |
| Resolution | 1.4Å |
| Reference | AUTH E.PAPAGRIGORIOU,E.SALAH,C.PHILLIPS,P.SAVITSKY,AUTH 2 P.BOISGUERIN,H.OSCHKINAT,C.GILEADI,X.YANG,AUTH 3 J.M.ELKINS,E.UGOCHUKWU,G.BUNKOCZI,J.UPPENBERG,AUTH 4 D.DOYLETITL CRYSTAL STRUCTURE OF THE 11TH PDZ DOMAIN OF MPDZTITL 2 (MUPP1).REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 85 |
| Number Of SNVs | 30 |
| Number Of Permutations | 1739 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.021 |
| p-value | 0.697 |
COSMIC
| Number Of Residues | 85 |
| Number Of SNVs | 4 |
| Number Of Permutations | 42 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.5 |
| p-value | 0.026 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 30 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.618 |
| p-value | 0.18 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
