General Structure Information
| PDB ID | 2qag |
| HGNC Gene Label(s) | SEPT6 |
| Structure Name | crystal structure of human septin trimer 2/6/7 |
| Resolution | 4.0Å |
| Reference | AUTH M.SIRAJUDDIN,M.FARKASOVSKY,F.HAUER,D.KUHLMANN,AUTH 2 I.G.MACARA,M.WEYAND,H.STARK,A.WITTINGHOFERTITL STRUCTURAL INSIGHT INTO FILAMENT FORMATION BYTITL 2 MAMMALIAN SEPTINS.REF NATURE V. 449 311 2007REFN ISSN 0028-0836PMID 17637674DOI 10.1038/NATURE06052 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 246 |
| Number Of SNVs | 37 |
| Number Of Permutations | 28736 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.177 |
| p-value | 0.62 |
COSMIC
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 37 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 26.0 |
| K Statistic | 0.509 |
| p-value | 0.395 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
