General Structure Information
| PDB ID | 2q8k |
| HGNC Gene Label(s) | PA2G4 |
| Structure Name | the crystal structure of ebp1 |
| Resolution | 1.6Å |
| Reference | AUTH E.KOWALINSKI,G.BANGE,B.BRADATSCH,E.HURT,K.WILD,I.SINNINGTITL THE CRYSTAL STRUCTURE OF EBP1 REVEALS A METHIONINETITL 2 AMINOPEPTIDASE FOLD AS BINDING PLATFORM FOR MULTIPLETITL 3 INTERACTIONS.REF FEBS LETT. V. 581 4450 2007REFN ISSN 0014-5793PMID 17765895DOI 10.1016/J.FEBSLET.2007.08.024 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 354 |
| Number Of SNVs | 35 |
| Number Of Permutations | 5531 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.205 |
| p-value | 0.066 |
COSMIC
| Number Of Residues | 354 |
| Number Of SNVs | 5 |
| Number Of Permutations | 270 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.4 |
| p-value | 0.254 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 35 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | -0.089 |
| p-value | 0.657 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
