General Structure Information
| PDB ID | 2psx |
| HGNC Gene Label(s) | KLK5 |
| Structure Name | crystal structure of human kallikrein 5 in complex with leupeptin |
| Resolution | 2.3Å |
| Reference | AUTH M.DEBELA,P.GOETTIG,V.MAGDOLEN,R.HUBER,N.M.SCHECHTER,W.BODETITL STRUCTURAL BASIS OF THE ZINC INHIBITION OF HUMAN TISSUETITL 2 KALLIKREIN 5.REF J.MOL.BIOL. V. 373 1017 2007REFN ISSN 0022-2836PMID 17881000DOI 10.1016/J.JMB.2007.08.042 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 223 |
| Number Of SNVs | 65 |
| Number Of Permutations | 19219 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.025 |
| p-value | 0.35 |
COSMIC
| Number Of Residues | 223 |
| Number Of SNVs | 7 |
| Number Of Permutations | 4473 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.333 |
| p-value | 0.952 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 65 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.237 |
| p-value | 0.368 |