2P02.A | MAT2A

PDB ID	2p02
HGNC Gene Label(s)	MAT2A
Structure Name	crystal structure of the alpha subunit of human s- adenosylmethionine synthetase 2
Resolution	1.21Å
Reference	AUTH E.PAPAGRIGORIOU,N.SHAFQAT,A.ROJKOVA,F.H.NIESSEN,AUTH 2 K.L.KAVANAGH,F.VON DELFT,F.GORREC,E.UGOCHUKWU,AUTH 3 C.H.ARROWSMITH,A.EDWARDS,J.WEIGELT,M.SUNDSTROM,AUTH 4 U.OPPERMANNTITL CRYSTAL STRUCTURE OF THE ALPHA SUBUNIT OF HUMANTITL 2 S-ADENOSYLMETHIONINE SYNTHETASE 2REF TO BE PUBLISHEDREFN

ExAC Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
2:85766457	rs146677669	G>D	A:38	(-6.20, 11.78, 6.80)
2:85768213		I>M	A:55	(4.29, 11.24, 45.16)
2:85768236		V>G	A:63	(14.75, 4.34, 47.88)
2:85768267		D>E	A:73	(25.45, -4.33, 42.90)
2:85768380	rs185115251	T>A	A:80	(5.33, 3.69, 47.26)
2:85768455		V>I	A:105	(10.38, 9.66, 52.25)
2:85768473		H>D	A:111	(11.72, 18.44, 45.38)
2:85768779		V>L	A:128	(6.87, 6.88, 57.24)
2:85768840		N>S	A:148	(29.28, -13.40, 34.63)
2:85769006		I>V	A:176	(3.33, 13.10, 25.97)
2:85769057		G>S	A:193	(5.20, 32.93, 42.80)
2:85769066		P>S	A:196	(0.57, 31.71, 44.63)
2:85769085		S>C	A:202	(-1.23, 18.13, 38.21)
2:85769303		R>Q	A:214	(3.70, 7.20, 4.96)
2:85769335		I>V	A:225	(-6.00, 21.74, 26.22)
2:85769341	rs141849127	I>V	A:227	(-5.35, 22.10, 32.76)
2:85769342	rs555524579	I>T	A:227	(-5.35, 22.10, 32.76)
2:85769371		L>F	A:237	(-13.04, 29.20, 38.31)
2:85769378		E>V	A:239	(-7.71, 34.34, 39.09)
2:85769404	rs373665984	V>I	A:248	(0.30, 27.79, 31.31)
2:85769442	rs369434466	E>D	A:260	(-10.89, 29.73, 17.04)
2:85769449	rs578215416	I>V	A:263	(-11.75, 22.62, 22.91)
2:85769450		I>T	A:263	(-11.75, 22.62, 22.91)
2:85769839		K>T	A:329	(18.01, 10.28, 15.03)
2:85769854		R>Q	A:334	(9.24, 9.23, 9.02)
2:85770027		S>A	A:341	(10.99, -10.99, 25.56)
2:85770060		I>V	A:352	(13.66, -9.26, 19.10)
2:85770095		S>R	A:363	(12.34, -5.08, 5.79)
2:85770099		R>G	A:365	(13.57, -9.13, 8.20)
2:85770121	rs371262419	K>M	A:372	(19.41, -9.49, 15.96)
2:85770150		I>V	A:382	(21.53, -3.19, 29.04)

2P02.A | MAT2A.