General Structure Information
| PDB ID | 2oj4 |
| HGNC Gene Label(s) | RGS3 |
| Structure Name | crystal structure of rgs3 rgs domain |
| Resolution | 2.3Å |
| Reference | AUTH L.REZABKOVA,E.BOURA,P.HERMAN,J.VECER,L.BOUROVA,M.SULC,AUTH 2 P.SVOBODA,V.OBSILOVA,T.OBSILTITL 14-3-3 PROTEIN INTERACTS WITH AND AFFECTS THE STRUCTURE OFTITL 2 RGS DOMAIN OF REGULATOR OF G PROTEIN SIGNALING 3 (RGS3).REF J.STRUCT.BIOL. V. 170 451 2010REFN ISSN 1047-8477PMID 20347994DOI 10.1016/J.JSB.2010.03.009 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 127 |
| Number Of SNVs | 32 |
| Number Of Permutations | 4205 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.044 |
| p-value | 0.401 |
COSMIC
| Number Of Residues | 127 |
| Number Of SNVs | 4 |
| Number Of Permutations | 833 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.167 |
| p-value | 0.471 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 32 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | -0.323 |
| p-value | 0.334 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
