General Structure Information
| PDB ID | 2ocp |
| HGNC Gene Label(s) | DGUOK |
| Structure Name | crystal structure of human deoxyguanosine kinase |
| Resolution | 2.8Å |
| Reference | AUTH K.JOHANSSON,S.RAMASWAMY,C.LJUNGKRANTZ,W.KNECHT,AUTH 2 J.PISKUR,B.MUNCH-PETERSEN,S.ERIKSSON,H.EKLUNDTITL STRUCTURAL BASIS FOR SUBSTRATE SPECIFICITIES OFTITL 2 CELLULAR DEOXYRIBONUCLEOSIDE KINASES.REF NAT.STRUCT.BIOL. V. 8 616 2001REFN ISSN 1072-8368PMID 11427893DOI 10.1038/89661 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 229 |
| Number Of SNVs | 60 |
| Number Of Permutations | 5813 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.076 |
| p-value | 0.765 |
ClinVar
| Number Of Residues | 229 |
| Number Of SNVs | 6 |
| Number Of Permutations | 509 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.467 |
| p-value | 0.53 |
COSMIC
| Number Of Residues | 229 |
| Number Of SNVs | 3 |
| Number Of Permutations | 27 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.667 |
| p-value | 0.573 |
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 60 |
| Number Of ClinVar SNVs | 6 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.227 |
| p-value | 0.596 |
Cosmic vs. ExAC
| Number Of ExAC SNVs | 60 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | 0.5 |
| p-value | 0.758 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
COSMIC PathProx Analysis
