General Structure Information
| PDB ID | 2nz0 |
| HGNC Gene Label(s) | KCND3 |
| Structure Name | crystal structure of potassium channel kv4.3 in complex with its regulatory subunit kchip1 (casp target) |
| Resolution | 3.2Å |
| Reference | AUTH H.WANG,Y.YAN,Q.LIU,Y.HUANG,Y.SHEN,L.CHEN,Y.CHEN,Q.YANG,AUTH 2 Q.HAO,K.WANG,J.CHAITITL STRUCTURAL BASIS FOR MODULATION OF KV4 K(+) CHANNELS BYTITL 2 AUXILIARY KCHIP SUBUNITS.REF NAT.NEUROSCI. V. 10 32 2007REFN ISSN 1097-6256PMID 17187064DOI 10.1038/NN1822 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 136 |
| Number Of SNVs | 23 |
| Number Of Permutations | 13703 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.451 |
| p-value | 0.801 |
COSMIC
| Number Of Residues | 136 |
| Number Of SNVs | 6 |
| Number Of Permutations | 2526 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.267 |
| p-value | 0.578 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 23 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.52 |
| p-value | 0.138 |