General Structure Information
| PDB ID | 2nyt |
| HGNC Gene Label(s) | APOBEC2 |
| Structure Name | the apobec2 crystal structure and functional implications for aid |
| Resolution | 2.5Å |
| Reference | AUTH C.PROCHNOW,R.BRANSTEITTER,M.G.KLEIN,M.F.GOODMAN,AUTH 2 X.S.CHENTITL THE APOBEC-2 CRYSTAL STRUCTURE AND FUNCTIONALTITL 2 IMPLICATIONS FOR THE DEAMINASE AID.REF NATURE V. 445 447 2007REFN ISSN 0028-0836PMID 17187054DOI 10.1038/NATURE05492 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 180 |
| Number Of SNVs | 58 |
| Number Of Permutations | 17116 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.106 |
| p-value | 0.772 |
COSMIC
| Number Of Residues | 180 |
| Number Of SNVs | 3 |
| Number Of Permutations | 109 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.667 |
| p-value | 0.184 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 58 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.501 |
| p-value | 0.225 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
