General Structure Information
| PDB ID | 2nn7 |
| HGNC Gene Label(s) | CA1 |
| Structure Name | structure of inhibitor binding to carbonic anhydrase i |
| Resolution | 1.85Å |
| Reference | AUTH D.K.SRIVASTAVA,K.M.JUDE,A.L.BANERJEE,M.HALDAR,AUTH 2 S.MANOKARAN,J.KOOREN,S.MALLIK,D.W.CHRISTIANSONTITL STRUCTURAL ANALYSIS OF CHARGE DISCRIMINATION INTITL 2 THE BINDING OF INHIBITORS TO HUMAN CARBONICTITL 3 ANHYDRASES I AND II.REF J.AM.CHEM.SOC. V. 129 5528 2007REFN ISSN 0002-7863PMID 17407288DOI 10.1021/JA068359W |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 257 |
| Number Of SNVs | 72 |
| Number Of Permutations | 10681 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.034 |
| p-value | 0.432 |
COSMIC
| Number Of Residues | 257 |
| Number Of SNVs | 3 |
| Number Of Permutations | 7 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.333 |
| p-value | 0.635 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
