General Structure Information
| PDB ID | 2nll |
| HGNC Gene Label(s) | THRB |
| Structure Name | retinoid x receptor-thyroid hormone receptor dna-binding domain heterodimer bound to thyroid response element dna |
| Resolution | 1.9Å |
| Reference | AUTH F.RASTINEJAD,T.PERLMANN,R.M.EVANS,P.B.SIGLERTITL STRUCTURAL DETERMINANTS OF NUCLEAR RECEPTORTITL 2 ASSEMBLY ON DNA DIRECT REPEATS.REF NATURE V. 375 203 1995REFN ISSN 0028-0836PMID 7746322DOI 10.1038/375203A0 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 101 |
| Number Of SNVs | 12 |
| Number Of Permutations | 9906 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.091 |
| p-value | 0.748 |
COSMIC
| Number Of Residues | 101 |
| Number Of SNVs | 3 |
| Number Of Permutations | 67 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | 0.333 |
| p-value | 0.933 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 12 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | -0.455 |
| p-value | 0.196 |