General Structure Information
| PDB ID | 2mbc |
| HGNC Gene Label(s) | PTP4A3 |
| Structure Name | solution structure of human holo-prl-3 in complex with vanadate |
| Resolution | -1.0Å |
| Reference | AUTH K.KIM,J.H.SONG,J.JEE,M.R.SHEEN,C.LEE,T.G.LEE,S.RO,J.M.CHO,AUTH 2 W.LEE,T.YAMAZAKI,Y.H.JEON,C.CHEONGTITL STRUCTURE OF HUMAN PRL-3, THE PHOSPHATASE ASSOCIATED WITHTITL 2 CANCER METASTASISREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 162 |
| Number Of SNVs | 34 |
| Number Of Permutations | 4312 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.078 |
| p-value | 0.369 |
COSMIC
| Number Of Residues | 162 |
| Number Of SNVs | 5 |
| Number Of Permutations | 313 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.1 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 34 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.147 |
| p-value | 0.618 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
