2M59.A | KDR

General Structure Information

PDB ID 2m59
HGNC Gene Label(s) KDR
Structure Name spatial structure of dimeric vegfr2 membrane domain in dpc micelles
Resolution -1.0Å
Reference AUTH K.S.MINEEV,A.S.ARSENIEV,M.A.SHULEPKO,E.N.LYUKMANOVATITL SPATIAL STRUCTURE OF DIMERIC VEGFR2 MEMBRANE DOMAIN IN DPCTITL 2 MICELLESREF TO BE PUBLISHEDREFN

Variant Set Distributions

ExAC Variants

Number Of Residues 37
Number Of SNVs 11
Number Of Permutations 1804
Optimal Distance Threshold 7.0
K Statistic 0.073
p-value 0.154
COSMIC

Number Of Residues 37
Number Of SNVs 3
Number Of Permutations 172
Optimal Distance Threshold 25.0
K Statistic 0.333
p-value 0.931

Ripley’s K Analysis Plots

ExACCOSMIC

Variant Set Comparisons

Cosmic vs. ExAC

Pathogenic Proximity Analysis

COSMIC PathProx Analysis

Mapped Variants

[+] ExAC Missense Variants

[+] COSMIC Missense Variants