General Structure Information
| PDB ID | 2lul |
| HGNC Gene Label(s) | TEC |
| Structure Name | solution nmr structure of ph domain of tyrosine-protein kinase tec from homo sapiens, northeast structural genomics consortium (nesg) target hr3504c |
| Resolution | -1.0Å |
| Reference | AUTH G.LIU,R.XIAO,H.JANJUA,K.HAMILTON,R.SHASTRY,E.KOHAN,AUTH 2 T.B.ACTON,J.K.EVERETT,H.LEE,K.PEDERSON,Y.J.HUANG,AUTH 3 G.T.MONTELIONETITL SOLUTION NMR STRUCTURE OF PH DOMAIN OF TYROSINE-PROTEINTITL 2 KINASE TEC FROM HOMO SAPIENS, NORTHEAST STRUCTURAL GENOMICSTITL 3 CONSORTIUM (NESG) TARGET HR3504CREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 154 |
| Number Of SNVs | 27 |
| Number Of Permutations | 9975 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.04 |
| p-value | 0.793 |
COSMIC
| Number Of Residues | 154 |
| Number Of SNVs | 4 |
| Number Of Permutations | 201 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.167 |
| p-value | 0.904 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 27 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | -0.49 |
| p-value | 0.173 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
