2LI8.A | LIN28A

PDB ID	2li8
HGNC Gene Label(s)	LIN28A
Structure Name	the solution structure of the lin28-znf domains bound to aggagau of pre-let-7 mirna
Resolution	-1.0Å
Reference	AUTH F.E.LOUGHLIN,L.F.GEBERT,H.TOWBIN,A.BRUNSCHWEIGER,J.HALL,AUTH 2 F.H.ALLAINTITL STRUCTURAL BASIS OF PRE-LET-7 MIRNA RECOGNITION BY THE ZINCTITL 2 KNUCKLES OF PLURIPOTENCY FACTOR LIN28.REF NAT.STRUCT.MOL.BIOL. V. 19 84 2011REFN ISSN 1545-9993PMID 22157959DOI 10.1038/NSMB.2202

ExAC Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
1:26751941		G>R	A:126	(12.87, -5.44, -2.15)
1:26751959	rs143830906	R>C	A:132	(10.62, 10.53, -3.32)
1:26751960	rs369619121	R>H	A:132	(10.62, 10.53, -3.32)
1:26751964	rs141858038	R>S	A:133	(4.38, 13.34, -5.89)
1:26751975		D>G	A:137	(6.78, 4.98, -7.98)
1:26752785		P>S	A:156	(-11.31, 1.72, -5.57)
1:26752829		M>I	A:170	(1.44, 1.83, 5.69)
1:26752831	rs201400954	V>E	A:171	(6.73, 1.35, 4.70)
1:26752833		A>S	A:172	(5.43, 4.14, 7.84)
1:26752837	COSM459390	S>L	A:173	(4.55, 1.17, 10.79)
1:26752843	rs376620145	P>L	A:175	(6.22, -5.15, 11.26)
1:26752855	rs369122240	Q>R	A:179	(13.96, -6.50, 11.89)
1:26752863	rs200820472	P>A	A:182	(16.06, 0.18, 11.07)
1:26752864		P>L	A:182	(16.06, 0.18, 11.07)
1:26752869		A>S	A:184	(19.46, 6.67, 11.29)

2LI8.A | LIN28A.