2L30.A | PARP1

General Structure Information

PDB ID 2l30
HGNC Gene Label(s) PARP1
Structure Name human parp-1 zinc finger 1
Resolution -1.0Å
Reference AUTH S.EUSTERMANN,H.VIDELER,J.YANG,P.T.COLE,D.GRUSZKA,AUTH 2 D.VERPREINTSEV,D.NEUHAUSTITL THE DNA-BINDING DOMAIN OF HUMAN PARP-1 INTERACTS WITH DNATITL 2 SINGLE-STRAND BREAKS AS A MONOMER THROUGH ITS SECOND ZINCTITL 3 FINGER.REF J.MOL.BIOL. 2011REFN ESSN 1089-8638DOI 10.1016/J.JMB.2011.01.034

Variant Set Distributions

ExAC Variants

Number Of Residues 108
Number Of SNVs 35
Number Of Permutations 2231
Optimal Distance Threshold 6.0
K Statistic 0.03
p-value 0.954

Mapped Variants

[+] ExAC Missense Variants