General Structure Information
| PDB ID | 2l27 |
| HGNC Gene Label(s) | CRHR1 |
| Structure Name | nmr structure of the ecd1 of crf-r1 in complex with a peptide agonist |
| Resolution | -1.0Å |
| Reference | AUTH C.R.GRACE,M.H.PERRIN,J.GULYAS,J.E.RIVIER,W.W.VALE,R.RIEKTITL NMR STRUCTURE OF THE FIRST EXTRACELLULAR DOMAIN OFTITL 2 CORTICOTROPIN-RELEASING FACTOR RECEPTOR 1 (ECD1-CRF-R1)TITL 3 COMPLEXED WITH A HIGH AFFINITY AGONIST.REF J.BIOL.CHEM. V. 285 38580 2010REFN ISSN 0021-9258PMID 20843795DOI 10.1074/JBC.M110.121897 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 84 |
| Number Of SNVs | 20 |
| Number Of Permutations | 3001 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.063 |
| p-value | 0.922 |