2JXB.A | NCK2

General Structure Information

PDB ID 2jxb
HGNC Gene Label(s) NCK2
Structure Name structure of cd3epsilon-nck2 first sh3 domain complex
Resolution -1.0Å
Reference AUTH K.TAKEUCHI,H.YANG,E.NG,S.Y.PARK,Z.Y.SUN,AUTH 2 E.L.REINHERZ,G.WAGNERTITL STRUCTURAL AND FUNCTIONAL EVIDENCE THAT NCKTITL 2 INTERACTION WITH CD3EPSILON REGULATES T-CELLTITL 3 RECEPTOR ACTIVITY.REF J.MOL.BIOL. V. 380 704 2008REFN ISSN 0022-2836PMID 18555270DOI 10.1016/J.JMB.2008.05.037

Variant Set Distributions

ExAC Variants

Number Of Residues 59
Number Of SNVs 11
Number Of Permutations 726
Optimal Distance Threshold 7.0
K Statistic 0.127
p-value 0.392

Mapped Variants

[+] ExAC Missense Variants