General Structure Information
| PDB ID | 2jwa |
| HGNC Gene Label(s) | ERBB2 |
| Structure Name | erbb2 transmembrane segment dimer spatial structure |
| Resolution | -1.0Å |
| Reference | AUTH E.V.BOCHAROV,K.S.MINEEV,P.E.VOLYNSKY,Y.S.ERMOLYUK,AUTH 2 E.N.TKACH,A.G.SOBOL,V.V.CHUPIN,M.P.KIRPICHNIKOV,AUTH 3 R.G.EFREMOV,A.S.ARSENIEVTITL SPATIAL STRUCTURE OF THE DIMERIC TRANSMEMBRANETITL 2 DOMAIN OF THE GROWTH FACTOR RECEPTOR ERBB2TITL 3 PRESUMABLY CORRESPONDING TO THE RECEPTOR ACTIVETITL 4 STATEREF J.BIOL.CHEM. V. 283 6950 2008REFN ISSN 0021-9258PMID 18178548DOI 10.1074/JBC.M709202200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 44 |
| Number Of SNVs | 9 |
| Number Of Permutations | 4693 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.083 |
| p-value | 0.137 |
COSMIC
| Number Of Residues | 44 |
| Number Of SNVs | 4 |
| Number Of Permutations | 799 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.333 |
| p-value | 0.141 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 9 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.444 |
| p-value | 0.326 |