General Structure Information
| PDB ID | 2jjs |
| HGNC Gene Label(s) | CD47 |
| Structure Name | structure of human cd47 in complex with human signal regulatory protein (sirp) alpha |
| Resolution | 1.85Å |
| Reference | AUTH D.HATHERLEY,S.C.GRAHAM,J.TURNER,K.HARLOS,AUTH 2 D.I.STUART,A.N.BARCLAYTITL PAIRED RECEPTOR SPECIFICITY EXPLAINED BYTITL 2 STRUCTURES OF SIGNAL REGULATORY PROTEINS ALONE ANDTITL 3 COMPLEXED WITH CD47.REF MOL.CELL V. 31 266 2008REFN ISSN 1097-2765PMID 18657508DOI 10.1016/J.MOLCEL.2008.05.026 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 115 |
| Number Of SNVs | 21 |
| Number Of Permutations | 6922 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.029 |
| p-value | 0.748 |
COSMIC
| Number Of Residues | 115 |
| Number Of SNVs | 3 |
| Number Of Permutations | 46 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC


Variant Set Comparisons
Cosmic vs. ExAC

Pathogenic Proximity Analysis
COSMIC PathProx Analysis

