General Structure Information
| PDB ID | 2jbm |
| HGNC Gene Label(s) | QPRT |
| Structure Name | qprtase structure from human |
| Resolution | 2.0Å |
| Reference | AUTH H.LIU,K.WOZNICA,G.CATTON,A.CRAWFORD,N.BOTTINF,AUTH 2 J.H.NAISMITHTITL STRUCTURAL AND KINETIC CHARACTERIZATION OFTITL 2 QUINOLINATE PHOSPHORIBOSYLTRANSFERASE (HQPRTASE)TITL 3 FROM HOMO SAPIENS.REF J.MOL.BIOL. V. 373 755 2007REFN ISSN 0022-2836PMID 17868694DOI 10.1016/J.JMB.2007.08.043 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 285 |
| Number Of SNVs | 76 |
| Number Of Permutations | 46767 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.179 |
| p-value | 0.106 |
COSMIC
| Number Of Residues | 285 |
| Number Of SNVs | 3 |
| Number Of Permutations | 18 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.667 |
| p-value | 0.3 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 76 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.706 |
| p-value | 0.235 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
