General Structure Information
| PDB ID | 2jaj |
| HGNC Gene Label(s) | DDAH1 |
| Structure Name | ddah1 complexed with l-257 |
| Resolution | 2.0Å |
| Reference | AUTH J.LEIPER,M.NANDI,B.TORONDEL,J.MURRAY-RUST,M.MALAKI,B.OHARA,AUTH 2 S.ROSSITER,S.ANTHONY,M.MADHANI,D.SELWOOD,C.SMITH,AUTH 3 B.WOJCIAK-STOTHARD,A.RUDIGER,R.STIDWILL,N.Q.MCDONALD,AUTH 4 P.VALLANCETITL DISRUPTION OF METHYLARGININE METABOLISM IMPAIRS VASCULARTITL 2 HOMEOSTASIS.REF NAT.MED. (N.Y.) V. 13 198 2007REFN ISSN 1078-8956PMID 17273169DOI 10.1038/NM1543 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 276 |
| Number Of SNVs | 53 |
| Number Of Permutations | 16999 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.075 |
| p-value | 0.407 |
COSMIC
| Number Of Residues | 276 |
| Number Of SNVs | 3 |
| Number Of Permutations | 1 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 53 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.35 |
| p-value | 0.423 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
