General Structure Information
| PDB ID | 2iik |
| HGNC Gene Label(s) | ACAA1 |
| Structure Name | crystal structure of human peroxisomal acetyl-coa acyl transferase 1 (acaa1) |
| Resolution | 2.55Å |
| Reference | AUTH E.PAPAGRIGORIOU,C.JOHANSSON,C.SMEE,K.KAVANAGH,A.C.W.PIKE,AUTH 2 M.SUNDSTROM,J.WEIGELT,A.EDWARDS,C.H.ARROWSMITH,O.GILEADI,AUTH 3 F.GORREC,C.UMEANO,F.VON DELFT,U.OPPERMANN,AUTH 4 STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL CRYSTAL STRUCTURE OF HUMAN PEROXISOMAL ACETYL-COA ACYLTITL 2 TRANSFERASE 1 (ACAA1)REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 390 |
| Number Of SNVs | 94 |
| Number Of Permutations | 14842 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.101 |
| p-value | 0.077 |
COSMIC
| Number Of Residues | 390 |
| Number Of SNVs | 6 |
| Number Of Permutations | 1178 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.333 |
| p-value | 0.723 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 94 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | -0.043 |
| p-value | 0.866 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
