General Structure Information
| PDB ID | 2ice |
| HGNC Gene Label(s) | VSIG4 |
| Structure Name | crig bound to c3c |
| Resolution | 3.1Å |
| Reference | AUTH C.WIESMANN,K.J.KATSCHKE,J.YIN,K.Y.HELMY,M.STEFFEK,AUTH 2 W.J.FAIRBROTHER,S.A.MCCALLUM,L.EMBUSCADO,L.DEFORGE,P.E.HASS,AUTH 3 M.VAN LOOKEREN CAMPAGNETITL STRUCTURE OF C3B IN COMPLEX WITH CRIG GIVES INSIGHTS INTOTITL 2 REGULATION OF COMPLEMENT ACTIVATION.REF NATURE V. 444 217 2006REFN ISSN 0028-0836PMID 17051150DOI 10.1038/NATURE05263 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 118 |
| Number Of SNVs | 30 |
| Number Of Permutations | 4186 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.085 |
| p-value | 0.606 |
COSMIC
| Number Of Residues | 118 |
| Number Of SNVs | 4 |
| Number Of Permutations | 573 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.167 |
| p-value | 0.788 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 30 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | -0.28 |
| p-value | 0.722 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
