General Structure Information
| PDB ID | 2hzq |
| HGNC Gene Label(s) | APOD |
| Structure Name | crystal structure of human apolipoprotein d (apod) in complex with progesterone |
| Resolution | 1.8Å |
| Reference | AUTH A.EICHINGER,A.NASREEN,H.J.KIM,A.SKERRATITL STRUCTURAL INSIGHT INTO THE DUAL LIGANDTITL 2 SPECIFICITY AND MODE OF HIGH DENSITY LIPOPROTEINTITL 3 ASSOCIATION OF APOLIPOPROTEIN D.REF J.BIOL.CHEM. V. 282 31068 2007REFN ISSN 0021-9258PMID 17699160DOI 10.1074/JBC.M703552200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 163 |
| Number Of SNVs | 42 |
| Number Of Permutations | 4209 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.016 |
| p-value | 0.3 |
COSMIC
| Number Of Residues | 163 |
| Number Of SNVs | 5 |
| Number Of Permutations | 933 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.1 |
| p-value | 0.894 |
Ripley’s K Analysis Plots
ExACCOSMIC


Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 42 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | -0.394 |
| p-value | 0.216 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis

