General Structure Information
| PDB ID | 2hw6 |
| HGNC Gene Label(s) | MKNK1 |
| Structure Name | crystal structure of mnk1 catalytic domain |
| Resolution | 2.5Å |
| Reference | AUTH R.JAUCH,M.K.CHO,C.NETTER,K.SCHREITER,B.AICHER,AUTH 2 M.ZWECKSTETTER,M.C.WAHLTITL MITOGEN-ACTIVATED PROTEIN KINASES INTERACTING KINASES ARETITL 2 AUTOINHIBITED BY A REPROGRAMMED ACTIVATION SEGMENT.REF EMBO J. V. 25 4020 2006REFN ISSN 0261-4189PMID 16917500DOI 10.1038/SJ.EMBOJ.7601285 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 242 |
| Number Of SNVs | 65 |
| Number Of Permutations | 38443 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.034 |
| p-value | 0.994 |