General Structure Information
| PDB ID | 2hv7 |
| HGNC Gene Label(s) | PPP2R4 |
| Structure Name | crystal structure of phosphotyrosyl phosphatase activator bound to atpgammas |
| Resolution | 2.5Å |
| Reference | AUTH Y.CHAO,Y.XING,Y.CHEN,Y.XU,Z.LIN,Z.LI,P.D.JEFFREY,AUTH 2 J.B.STOCK,Y.SHITITL STRUCTURE AND MECHANISM OF THE PHOSPHOTYROSYLTITL 2 PHOSPHATASE ACTIVATOR.REF MOL.CELL V. 23 535 2006REFN ISSN 1097-2765PMID 16916641DOI 10.1016/J.MOLCEL.2006.07.027 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 301 |
| Number Of SNVs | 62 |
| Number Of Permutations | 7418 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.03 |
| p-value | 0.219 |
COSMIC
| Number Of Residues | 301 |
| Number Of SNVs | 5 |
| Number Of Permutations | 336 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.1 |
| p-value | 0.677 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 62 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | -0.155 |
| p-value | 0.457 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
