General Structure Information
| PDB ID | 2hdh |
| HGNC Gene Label(s) | HADH |
| Structure Name | biochemical characterization and structure determination of human heart short chain l-3-hydroxyacyl coa dehydrogenase provide insight into catalytic mechanism |
| Resolution | 2.2Å |
| Reference | AUTH J.J.BARYCKI,L.K.OBRIEN,J.M.BRATT,R.ZHANG,R.SANISHVILI,AUTH 2 A.W.STRAUSS,L.J.BANASZAKTITL BIOCHEMICAL CHARACTERIZATION AND CRYSTAL STRUCTURETITL 2 DETERMINATION OF HUMAN HEART SHORT CHAIN L-3-HYDROXYACYL-COATITL 3 DEHYDROGENASE PROVIDE INSIGHTS INTO CATALYTIC MECHANISM.REF BIOCHEMISTRY V. 38 5786 1999REFN ISSN 0006-2960PMID 10231530DOI 10.1021/BI9829027 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 284 |
| Number Of SNVs | 79 |
| Number Of Permutations | 14024 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.072 |
| p-value | 0.153 |
ClinVar
| Number Of Residues | 284 |
| Number Of SNVs | 4 |
| Number Of Permutations | 429 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.333 |
| p-value | 0.214 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 79 |
| Number Of ClinVar SNVs | 4 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.14 |
| p-value | 0.288 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
