General Structure Information
| PDB ID | 2gry |
| HGNC Gene Label(s) | KIF2A |
| Structure Name | crystal structure of the human kif2 motor domain in complex with adp |
| Resolution | 2.35Å |
| Reference | AUTH J.WANG,Y.SHEN,W.TEMPEL,R.LANDRY,C.H.ARROWSMITH,A.M.EDWARDS,AUTH 2 M.SUNDSTROM,J.WEIGELT,A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF THE HUMAN KIF2 MOTOR DOMAIN IN COMPLEXTITL 2 WITH ADPREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 327 |
| Number Of SNVs | 21 |
| Number Of Permutations | 5265 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.143 |
| p-value | 0.934 |
COSMIC
| Number Of Residues | 327 |
| Number Of SNVs | 4 |
| Number Of Permutations | 16 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.167 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 21 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 26.0 |
| K Statistic | 0.41 |
| p-value | 0.547 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
