General Structure Information
| PDB ID | 2ggz |
| HGNC Gene Label(s) | GUCA1C |
| Structure Name | crystal structure of human guanylate cyclase activating protein-3 |
| Resolution | 3.0Å |
| Reference | AUTH R.STEPHEN,K.PALCZEWSKI,M.C.SOUSATITL THE CRYSTAL STRUCTURE OF GCAP3 SUGGESTS MOLECULARTITL 2 MECHANISM OF GCAP-LINKED CONE DYSTROPHIES.REF J.MOL.BIOL. V. 359 266 2006REFN ISSN 0022-2836PMID 16626734DOI 10.1016/J.JMB.2006.03.042 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 165 |
| Number Of SNVs | 45 |
| Number Of Permutations | 4934 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.037 |
| p-value | 0.66 |
COSMIC
| Number Of Residues | 165 |
| Number Of SNVs | 3 |
| Number Of Permutations | 108 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.333 |
| p-value | 0.816 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 45 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 25.0 |
| K Statistic | -0.376 |
| p-value | 0.875 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
