General Structure Information
| PDB ID | 2fze |
| HGNC Gene Label(s) | ADH5 |
| Structure Name | crystal structure of the binary complex of human glutathione-dependent formaldehyde dehydrogenase with adp- ribose |
| Resolution | 1.9Å |
| Reference | AUTH P.C.SANGHANI,W.I.DAVIS,L.ZHAI,H.ROBINSONTITL STRUCTURE-FUNCTION RELATIONSHIPS IN HUMANTITL 2 GLUTATHIONE-DEPENDENT FORMALDEHYDE DEHYDROGENASE.TITL 3 ROLE OF GLU-67 AND ARG-368 IN THE CATALYTICTITL 4 MECHANISM.REF BIOCHEMISTRY V. 45 4819 2006REFN ISSN 0006-2960PMID 16605250DOI 10.1021/BI052554Q |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 373 |
| Number Of SNVs | 82 |
| Number Of Permutations | 15915 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.036 |
| p-value | 0.623 |
COSMIC
| Number Of Residues | 373 |
| Number Of SNVs | 3 |
| Number Of Permutations | 7 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.333 |
| p-value | 0.399 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
