General Structure Information
| PDB ID | 2fyt |
| HGNC Gene Label(s) | PRMT3 |
| Structure Name | human hmt1 hnrnp methyltransferase-like 3 (s. cerevisiae) protein |
| Resolution | 2.0Å |
| Reference | AUTH H.WU,J.R.MIN,H.ZENG,P.LOPPNAU,M.SUNDSTROM,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,A.BOCHKAREV,A.N.PLOTNIKOVTITL THE CRYSTAL STRUCTURE OF HUMAN HMT1 HNRNPTITL 2 METHYLTRANSFERASE-LIKE 3 IN COMPLEX WITH SAH.REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 311 |
| Number Of SNVs | 83 |
| Number Of Permutations | 16229 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.101 |
| p-value | 0.154 |
COSMIC
| Number Of Residues | 311 |
| Number Of SNVs | 3 |
| Number Of Permutations | 269 |
| Optimal Distance Threshold | 49.0 |
| K Statistic | 0.667 |
| p-value | 0.396 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 83 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 28.0 |
| K Statistic | -0.54 |
| p-value | 0.119 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
