2F9M.A | RAB11B

General Structure Information

PDB ID 2f9m
HGNC Gene Label(s) RAB11B
Structure Name 3d structure of active human rab11b gtpase
Resolution 1.95Å
Reference AUTH S.M.SCAPIN,F.R.CARNEIRO,A.C.ALVES,F.J.MEDRANO,AUTH 2 B.G.GUIMARAES,N.I.ZANCHINTITL THE CRYSTAL STRUCTURE OF THE SMALL GTPASE RAB11BTITL 2 REVEALS CRITICAL DIFFERENCES RELATIVE TO THETITL 3 RAB11A ISOFORM.REF J.STRUCT.BIOL. V. 154 260 2006REFN ISSN 1047-8477PMID 16545962DOI 10.1016/J.JSB.2006.01.007

Variant Set Distributions

ExAC Variants

Number Of Residues 181
Number Of SNVs 24
Number Of Permutations 4152
Optimal Distance Threshold 7.0
K Statistic 0.058
p-value 0.515
COSMIC

Number Of Residues 181
Number Of SNVs 3
Number Of Permutations 108
Optimal Distance Threshold 16.0
K Statistic 0.667
p-value 0.451

Ripley’s K Analysis Plots

ExACCOSMIC

Variant Set Comparisons

Cosmic vs. ExAC

Number Of ExAC SNVs 24
Number Of COSMIC SNVs 3
Optimal Distance Threshold 16.0
K Statistic 0.413
p-value 0.447

Pathogenic Proximity Analysis

COSMIC PathProx Analysis

Mapped Variants

[+] ExAC Missense Variants

[+] COSMIC Missense Variants