General Structure Information
| PDB ID | 2f6q |
| HGNC Gene Label(s) | ECI2 |
| Structure Name | the crystal structure of human peroxisomal delta3, delta2 enoyl coa isomerase (peci) |
| Resolution | 1.95Å |
| Reference | AUTH A.TURNBULL,P.LUKACIK,N.SHAFQAT,C.SMEE,G.BERRIDGE,K.GUO,AUTH 2 F.VON DELFT,J.WEIGELT,M.SUNDSTROM,C.ARROWSMITH,A.EDWARDS,AUTH 3 O.GILEADI,U.OPPERMANNTITL THE CRYSTAL STRUCTURE OF HUMAN PEROXISOMAL DELTA3, DELTA2TITL 2 ENOYL COA ISOMERASE (PECI)REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 247 |
| Number Of SNVs | 74 |
| Number Of Permutations | 27405 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.314 |
| p-value | 0.137 |
COSMIC
| Number Of Residues | 247 |
| Number Of SNVs | 4 |
| Number Of Permutations | 186 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.167 |
| p-value | 0.725 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 74 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | -0.435 |
| p-value | 0.179 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
