General Structure Information
| PDB ID | 2edd |
| HGNC Gene Label(s) | DCC |
| Structure Name | solution structure of the fifth fibronectin type iii domain of human netrin receptor dcc |
| Resolution | -1.0Å |
| Reference | AUTH N.TOCHIO,S.KOSHIBA,T.TOMIZAWA,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIFTH FIBRONECTIN TYPETITL 2 III DOMAIN OF HUMAN NETRIN RECEPTOR DCCREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 110 |
| Number Of SNVs | 24 |
| Number Of Permutations | 10259 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.391 |
| p-value | 0.082 |
COSMIC
| Number Of Residues | 110 |
| Number Of SNVs | 4 |
| Number Of Permutations | 1037 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.167 |
| p-value | 0.595 |
Ripley’s K Analysis Plots
ExACCOSMIC


Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 24 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | -0.384 |
| p-value | 0.268 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis

