2ECB.A | ZHX1

General Structure Information

PDB ID 2ecb
HGNC Gene Label(s) ZHX1
Structure Name the solution structure of the third homeobox domain of human zinc fingers and homeoboxes protein
Resolution -1.0Å
Reference AUTH S.OHNISHI,N.TOCHIO,A.SASAGAWA,K.SAITO,S.KOSHIBA,AUTH 2 M.INOUE,T.KIGAWA,S.YOKOYAMATITL THE SOLUTION STRUCTURE OF THE THIRD HOMEOBOXTITL 2 DOMAIN OF HUMAN ZINC FINGERS AND HOMEOBOXES PROTEINREF TO BE PUBLISHEDREFN

Variant Set Distributions

ExAC Variants

Number Of Residues 76
Number Of SNVs 18
Number Of Permutations 14856
Optimal Distance Threshold 19.0
K Statistic 0.399
p-value 0.335
COSMIC

Number Of Residues 76
Number Of SNVs 3
Number Of Permutations 1
Optimal Distance Threshold 8.0
K Statistic 0.333
p-value 1.0

Ripley’s K Analysis Plots

ExACCOSMIC

Variant Set Comparisons

Cosmic vs. ExAC

Number Of ExAC SNVs 18
Number Of COSMIC SNVs 3
Optimal Distance Threshold 11.0
K Statistic 0.516
p-value 0.094

Pathogenic Proximity Analysis

COSMIC PathProx Analysis

Mapped Variants

[+] ExAC Missense Variants

[+] COSMIC Missense Variants