General Structure Information
| PDB ID | 2dlw |
| HGNC Gene Label(s) | DOK2 |
| Structure Name | solution structure of the irs domain of human docking protein 2, isoform a |
| Resolution | -1.0Å |
| Reference | AUTH H.P.ZHANG,C.KUROSAKI,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE IRS DOMAIN OF HUMANTITL 2 DOCKING PROTEIN 2, ISOFORM AREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 100 |
| Number Of SNVs | 33 |
| Number Of Permutations | 2195 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.178 |
| p-value | 0.032 |
COSMIC
| Number Of Residues | 100 |
| Number Of SNVs | 4 |
| Number Of Permutations | 1 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 33 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | -0.216 |
| p-value | 0.836 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
