General Structure Information
| PDB ID | 2dlh |
| HGNC Gene Label(s) | PTPRD |
| Structure Name | solution structure of the second fn3 domain of human receptor-type tyrosine-protein phosphatase delta |
| Resolution | -1.0Å |
| Reference | AUTH K.SEIMIYA,F.HAYASHI,M.YOSHIDA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND FN3 DOMAIN OFTITL 2 HUMAN RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASETITL 3 DELTAREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 108 |
| Number Of SNVs | 25 |
| Number Of Permutations | 5996 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.047 |
| p-value | 0.408 |
COSMIC
| Number Of Residues | 108 |
| Number Of SNVs | 3 |
| Number Of Permutations | 46 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 25 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 27.0 |
| K Statistic | -0.41 |
| p-value | 0.517 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
