2D68.A | FGFR1OP

PDB ID	2d68
HGNC Gene Label(s)	FGFR1OP
Structure Name	structure of the n-terminal domain of fop (fgfr1op) protein
Resolution	1.6Å
Reference	AUTH A.MIKOLAJKA,X.YAN,G.M.POPOWICZ,P.SMIALOWSKI,AUTH 2 E.A.NIGG,T.A.HOLAKTITL STRUCTURE OF THE N-TERMINAL DOMAIN OF THE FOPTITL 2 (FGFR1OP) PROTEIN AND IMPLICATIONS FOR ITSTITL 3 DIMERIZATION AND CENTROSOMAL LOCALIZATION.REF J.MOL.BIOL. V. 359 863 2006REFN ISSN 0022-2836PMID 16690081DOI 10.1016/J.JMB.2006.03.070

ExAC Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
6:167416712	rs17856383	K>R	A:63	(14.47, 3.90, 6.31)
6:167416714		K>E	A:64	(15.24, 8.26, 4.26)
6:167416718		F>C	A:65	(15.10, 11.04, 10.91)
6:167416721		L>S	A:66	(16.50, 6.56, 11.65)
6:167416724		N>T	A:67	(20.49, 6.72, 7.58)
6:167417213	rs200312790	R>C	A:72	(20.80, 6.72, 15.89)
6:167417214	rs377028909	R>H	A:72	(20.80, 6.72, 15.89)
6:167417217		L>S	A:73	(21.04, 11.81, 18.08)
6:167417234	rs201515841	A>T	A:79	(13.75, 6.37, 23.86)
6:167417238		E>A	A:80	(16.23, 8.42, 27.59)
6:167417239		E>D	A:80	(16.23, 8.42, 27.59)
6:167417240		F>V	A:81	(10.89, 10.84, 27.74)
6:167417246		Q>K	A:83	(13.98, 3.95, 28.70)
6:167417266	rs140062109	F>L	A:89	(2.47, -0.74, 28.29)
6:167417294		S>G	A:99	(11.82, -0.45, 12.84)
6:167417768		G>D	A:106	(22.21, 4.86, 25.08)
6:167417774		E>G	A:108	(27.31, 5.95, 28.87)
6:167417775	rs150980464	E>D	A:108	(27.31, 5.95, 28.87)
6:167417776		N>D	A:109	(26.92, 6.07, 24.45)
6:167417786	rs139592603	R>Q	A:112	(29.78, 9.81, 24.32)
6:167417788		D>N	A:113	(27.14, 11.54, 21.35)
6:167417797		I>V	A:116	(25.51, 15.81, 28.36)
6:167417800	rs149745085	I>V	A:117	(29.10, 16.23, 31.78)
6:167417807		A>V	A:119	(25.62, 14.91, 37.30)
6:167417816		T>S	A:122	(21.81, 15.39, 34.94)
6:167417824	rs147838580	G>R	A:125	(16.54, 13.33, 34.13)
6:167417825		G>E	A:125	(16.54, 13.33, 34.13)
6:167417851	rs528148538 COSM1075936	R>C	A:134	(22.54, 23.74, 28.58)

2D68.A | FGFR1OP.