General Structure Information
| PDB ID | 2crp |
| HGNC Gene Label(s) | RGS5 |
| Structure Name | solution structure of the rgs domain of regulator of g- protein signalling 5 (rgs 5) |
| Resolution | -1.0Å |
| Reference | AUTH H.P.ZHANG,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RGS DOMAIN OF REGULATORTITL 2 OF G-PROTEIN SIGNALLING 5 (RGS 5)REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 137 |
| Number Of SNVs | 34 |
| Number Of Permutations | 17284 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.032 |
| p-value | 0.872 |
COSMIC
| Number Of Residues | 137 |
| Number Of SNVs | 4 |
| Number Of Permutations | 445 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.167 |
| p-value | 0.919 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 34 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | -0.278 |
| p-value | 0.694 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
