2CPE.A | EWSR1

PDB ID	2cpe
HGNC Gene Label(s)	EWSR1
Structure Name	solution structure of the rna recognition motif of ewing sarcoma(ews) protein
Resolution	-1.0Å
Reference	AUTH T.NAGATA,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RNA RECOGNITION MOTIF OFTITL 2 EWING SARCOMA(EWS) PROTEINREF TO BE PUBLISHEDREFN

ExAC Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
22:29688515		A>S	A:362	(2.17, 4.72, 1.29)
22:29688518		I>V	A:363	(0.37, 0.80, -0.93)
22:29688549		T>N	A:373	(12.04, -9.84, -6.63)
22:29688555		D>G	A:375	(12.57, -5.27, -9.75)
22:29688574		F>L	A:381	(3.11, -2.69, -6.32)
22:29688577		K>N	A:382	(4.68, 0.64, -13.40)
22:29688579		Q>R	A:383	(-0.09, -2.58, -12.94)
22:29688588		V>A	A:386	(4.25, 6.56, -11.34)
22:29692232		N>Y	A:390	(15.30, 7.74, -5.01)
22:29692236		K>R	A:391	(16.05, 12.63, -5.84)
22:29692241		T>A	A:393	(19.18, 6.03, -5.07)
22:29692247	COSM160849	Q>K	A:395	(16.63, 2.16, -6.19)
22:29692253		M>V	A:397	(10.91, 4.90, -2.41)
22:29692266		Y>C	A:401	(8.98, -5.53, 5.76)
22:29692298	COSM1033131 COSM1592922	D>N	A:412	(5.26, -8.24, 4.38)
22:29692311		S>F	A:416	(6.13, 4.70, -1.27)
22:29692322		P>A	A:420	(-1.80, 11.24, -1.90)
22:29692328	rs200360700	T>A	A:422	(-1.52, 7.17, -7.10)
22:29692340	rs140488021	A>S	A:426	(-3.11, 1.72, -5.80)
22:29692343	rs538447999	V>M	A:427	(-5.01, 0.47, -1.69)
22:29693819		K>Q	A:433	(-4.23, -7.76, -8.30)
22:29693835		S>T	A:438	(-0.19, -15.79, -3.89)
22:29693859	rs200670756	R>Q	A:446	(-0.46, 7.38, 9.32)
22:29693865		K>T	A:448	(-7.13, 4.35, 13.58)
22:29693866		K>N	A:448	(-7.13, 4.35, 13.58)
22:29693873	rs201802087	M>V	A:451	(-13.70, 10.68, 18.17)

2CPE.A | EWSR1.