General Structure Information
| PDB ID | 2cmw |
| HGNC Gene Label(s) | CSNK1G1 |
| Structure Name | structure of human casein kinase 1 gamma-1 in complex with 2-(2-hydroxyethylamino)-6-(3-chloroanilino)-9- isopropylpurine (casp target) |
| Resolution | 1.75Å |
| Reference | AUTH G.BUNKOCZI,P.RELLOS,S.DAS,P.SAVITSKY,F.NIESEN,F.SOBOTT,AUTH 2 O.FEDOROV,A.C.W.PIKE,F.VON DELFT,M.SUNDSTROM,C.ARROWSMITH,AUTH 3 A.EDWARDS,J.WEIGELT,S.KNAPPTITL STRUCTURE OF HUMAN CASEIN KINASE 1 GAMMA-1 IN COMPLEX WITHTITL 2 2-(2-HYDROXYETHYLAMINO)-6-TITL 3 (3-CHLOROANILINO)-9-ISOPROPYLPURINE (CASP TARGET)REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 293 |
| Number Of SNVs | 48 |
| Number Of Permutations | 5864 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.011 |
| p-value | 0.896 |
COSMIC
| Number Of Residues | 293 |
| Number Of SNVs | 4 |
| Number Of Permutations | 768 |
| Optimal Distance Threshold | 46.0 |
| K Statistic | 0.833 |
| p-value | 0.568 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 48 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | -0.402 |
| p-value | 0.081 |