General Structure Information
| PDB ID | 2c9y |
| HGNC Gene Label(s) | AK2 |
| Structure Name | structure of human adenylate kinase 2 |
| Resolution | 2.1Å |
| Reference | AUTH G.BUNKOCZI,P.FILIPPAKOPOULOS,J.E.DEBRECZENI,A.TURNBULL,AUTH 2 E.PAPAGRIGORIOU,P.SAVITSKY,S.COLEBROOK,F.VON DELFT,AUTH 3 C.ARROWSMITH,A.EDWARDS,M.SUNDSTROM,J.WEIGELT,S.KNAPPTITL STRUCTURE OF HUMAN ADENYLATE KINASE 2REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 218 |
| Number Of SNVs | 58 |
| Number Of Permutations | 22303 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.064 |
| p-value | 0.3 |
ClinVar
| Number Of Residues | 218 |
| Number Of SNVs | 4 |
| Number Of Permutations | 622 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.167 |
| p-value | 0.224 |
COSMIC
| Number Of Residues | 218 |
| Number Of SNVs | 5 |
| Number Of Permutations | 980 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.5 |
| p-value | 0.42 |
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 58 |
| Number Of ClinVar SNVs | 4 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.135 |
| p-value | 0.198 |
Cosmic vs. ExAC
| Number Of ExAC SNVs | 58 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.285 |
| p-value | 0.267 |