General Structure Information
| PDB ID | 2bzl |
| HGNC Gene Label(s) | PTPN14 |
| Structure Name | crystal structure of the human protein tyrosine phosphatase n14 at 1.65 a resolution |
| Resolution | 1.65Å |
| Reference | AUTH A.J.BARR,J.E.DEBRECZENI,J.ESWARAN,S.KNAPPTITL CRYSTAL STRUCTURE OF HUMAN PROTEIN TYROSINETITL 2 PHOSPHATASE 14 (PTPN14) AT 1.65-A RESOLUTION.REF PROTEINS V. 63 1132 2006REFN ISSN 0887-3585PMID 16534812DOI 10.1002/PROT.20958 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 284 |
| Number Of SNVs | 62 |
| Number Of Permutations | 32008 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.086 |
| p-value | 0.103 |
COSMIC
| Number Of Residues | 284 |
| Number Of SNVs | 5 |
| Number Of Permutations | 764 |
| Optimal Distance Threshold | 29.0 |
| K Statistic | 0.4 |
| p-value | 0.37 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 62 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | -0.379 |
| p-value | 0.393 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
